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HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulphonic acid), powder acid-free, Corning®

Supplier: MEDIATECH INC

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Synonyms: 4-(2-Hydroxyethyl)piperazin-1-ylethanesulphonic acid , 2-(4-(2-Hydroxyethyl)piperazin-1-yl)ethanesulphonic acid , N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulphonic acid) , N-2-Hydroxyethylpiperazine-N′-2-ethanesulphonic acid , HEPES free acid

MDTC61-034-RREA 22766.58 INR InStock
MDTC61-034-RR MDTC61-034-RO MDTC61-034-RM
HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulphonic acid), powder acid-free, Corning®
HEPES (4-(2-Hydroxyethyl)piperazin-1-ylethanesulphonic acid)
HEPES (N-2-hydroxyethylpiperazine-N’-2-ethanesulphonic acid) provides an alternative to the use of bicarbonate for buffering because it does not require elevated levels of CO2

Unlike the low pKa of bicarbonate, HEPES has a pKa of 7.66 making it a much stronger buffer in the pH 7.2-7.6 range than bicarbonate buffer. Potential disadvantages of HEPES include toxicity over 100 mM and lack of nutritive value to the cell.


Formula: C₈H₁₈N₂O₄S
MW: 238,31 g/mol
Melting Pt: 210 to 215 °C
Density: 1,448 g/cm³ (20 °C)
Storage Temperature: Ambient
 MDL Number: MFCD00006158
CAS Number: 7365-45-9
EINECS: 230-907-9
UN: 0000
Merck Index: 13,04672
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