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Downstream purification for cell therapy

Comparing downstream purification approaches between cell therapies and other biologics is quite different.

Methods required to obtain the final cell dose with the required quality parameters include: 

  • Centrifugation for removal of debris, washing, and concentration of the cell dose, 
  • Alternatives to centrifugation, such as counter-flow centrifugation, and 
  • Depth and ultrafiltration using TFF options.

Explore solutions for downstream purification of cell therapy

Biopharma Production Chemicals and Excipients

Single-use Solutions

Environmental control

Preparation of buffers

Downstream process optimization support

Explore product choices for downstream purification of cell therapy

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